Without a doubt Caddyshack.

1. Ghostbusters
1-A Caddyshack

tough to leave out Groundhog Day and GB2

Meatballs

Ghostbusters, What About Bob?, or Scrooged.

Quick Change for me. Never gets old.

He was never better than as "Big Ern McCracken" in Kignpin....

Ghostbusters.

Its probably my favorite film of all time. Its been a favorite since I was a kid and still is, one movie I never get tired of seeing.

Wild Things

What About Bob? followed by Ghostbusters and Groundhog Day. I think Caddyshack is one of the most overrated movies of all time, it sucks.

What About Bob? is one of the funniest movies ever made, it never gets old and is endlessly quotable.

Life Aquatic

I voted for Groundhog Day, though Tootsie would be my pick, though he's not the lead.

I just watched this recently and I didn't think it had aged well at all. Murray's wise ass character just didn't seem funny anymore.

Stripes is my favorite.

That Canadian classic that spawned a handful of 'balls' movies up North; Meatballs.

From that list:
Ghostbusters
Rushmore
What About Bob
Kingpin

It is so hard to pick from Caddyshack, Stripes, and Ghostbusters, as they rank in my Top 10 comedies of all-time.

Even though I have seen Caddyshack more times then any other comedy, Ghostbusters was made for Bill Murray, so I will go with it.

Broken Flowers. Plus I love Jim Jarmusch.

Rushmore even though its more of an ensemble cast, love Lost in Translation too.

Actually it was made for John Belushi

This is a tough one. I like his role in Caddyshack the most, but Rodney Dangerfield really irks me. Stripes and Groundhog Day are both great, almost wholly because of Murray. Ghostbusters, though, is probably my favorite movie, out of those listed.

1.Ghostbusters
2.Quick Change

Groundhog Day.

I picked What About Bob. Stripes 2nd. Caddyshack 3rd.
Groundhog day was terrible I thought.

My favorite is definitely Scrooged, with Groundhog Day a close second.

Rob

Groundhog Day