I'm left handed but I don't play southpaw or inverted. I used to in Halo 2 but for whatever reason (maybe lack of support in some titles) I stopped. I was just curious about the breakdown.

I am also left-handed but do everything right-handed when gaming (including Rock Band) EXCEPT for Wii Sports.

I play Rock Band right handed as well. When I first picked up the game I tried to play leftie but I sucked no matter how I held the guitar. I just kept practicing right handed and now that's what I like. Go figure.

Also true - anything with the wii (that uses waggle controls) I will have the wiimote in my left and the nunchuck in the right.

I typically lean to the right. Southpaw is for Liberals.

Southpaw and play der RockBand southpaw too.

Right-handed, standard controls, inverted y-axis.

Have never switched how I play games due to being a lefty, even Rock Band (that has more to do with me actually playing guitar/bass right handed). Wii Sports does get switched over to left though.

I'm lefthanded here as well. I write and throw with my left hand and applicably this translates to various Wii Sports games (except I am righty in Bowling). However for Rock Band, I play as is.

I play drums on RB lefty, but everything else is regular.

Lefty. Play guitar and drum righty. I would think I'd play Wii Sports lefty, but I don't have a Wii.

I'm left-handed. It depends on the game. But I hate it when games don't have a lefty-flip option as I like to hold the wiimote in my left hand and the nunchuck in my right. Punch-Out lost favor with me because of that.

Righty.

I used to rock inverted in Goldeneye, Turok and Perfect Dark, but in the transition to a second analog with Halo, I somehow converted to standard.

Right. Play inverted y-axis.