Quagmire: Hey there sweetie, how old are you?
girl: 16
Quagmire: 18? Your first!
girl: MOM!
Quagmire: I like where this is going! Giggady Giggady Gig-a-dee!

WE HAVE A WINNA!!!!!! rotfl :lol: rotfl :lol:

That scene is priceless.

Quagmire: I felt guilty once, but then she woke up halfway through.

Quagmire: Wait a minute, you pulled me away from a Swedish girly-girl and her paralyzed but trusting cousin for this?

Quagmire: I've never done it with a Spanish chick before... hehe, ooolééé...

Brian: And you made love to two Filipino women... <sniff> and a man...
Quagmire: You mean, you mean three Filipino women.... oh, oh God!

Awwww riiiiiiight......

Stewie: "Do you know what today is? It's a bad day to be a sperm!!"

From the same episode as the quote above:

Bertram (Stewie's sperm brother): I know many things
Stewie: Indeed
Bertram: Quite
Stewie: Yes
Bertram: Hmmm
Stewie: Well perhaps we shall exchange monosyllabic expressions of arrogance in person
Bertram: Ah
Stewie: Hmmm
Bertram: Yes

Another good one:
Peter: I'm as uncompetitive as anyone, in fact, I'm the most uncompetitive, so I win.

quadmire: "common 'Women I gave the Clap To!'"

Well, not really a quote you can use, but I always loved the scene where Peter's sneaking out of his window and falls, only to have Spider Man shoot a web right under him.

Peter: Thanks Spider Man!
Spider Man: Everybody gets one.

Chris: [mimes taking Peter's nose] Got yer nose!
Peter: [ slowly rips off Chris's face] Got yer face! Ha-ha-ha!

Does this look like a Q to you?

Everyman has their santuary. Catholics have the church, Fat people have Wisconsin, and I've got the brewry....