EXCLUSIVE: Robert De Niro, Ben Stiller, Teri Polo and Blythe Danner are in early talks to return for a new film in the Meet the Parents franchise, in development at Universal Pictures.

Plot details are being kept inside the circle of trust. John Hamburg — who co-wrote all three prior films in the franchise, and produced the most recent, Little Fockers — is set to write the screenplay. No word yet on who’s directing.

Jane Rosenthal and De Niro are returning to produce through Tribeca Productions, along with Jay Roach — who directed the first two films and produced all three past installments — through Delirious Media. Stiller and John Lesher will also produce through Red Hour Films. Executive Vice President of Production Development Matt Reilly and Director of Production Development Jacqueline Garrell will oversee the project for the studio.

A comedy juggernaut hinging on uncomfortable situations with in-laws, Meet the Parents centers on the hilariously awkward and tension-filled dynamics between male nurse Greg Focker (Stiller) and his intimidating, ex-CIA father-in-law, Jack Byrnes (De Niro), watching as the dynamic between them both evolves and stays the same, as Greg marries Jack’s daughter, Pam (Polo), and has children with her. Also a core cast member, Danner plays Jack’s wife, Dina. While Dustin Hoffman and Barbra Streisand also appeared in multiple films as Greg’s parents, Bernie and Roz — along with Owen Wilson as Pam’s ex-boyfriend, Kevin — it’s not yet clear whether they’ll return.

Meet the Parents was critically acclaimed upon its release and grossed over $330 million worldwide, becoming the seventh highest grossing film globally in 2000. Sequels Meet the Fockers (2004) and Little Fockers (2010) followed and were also box office successes, culminating in a total franchise gross of over $1.13 billion.