spider-man, which issues make up the second movie?
 

from what i hear, like with daredevil, that the second spider-man movie is based on the comics during a specific run, anyone know what run that is?

I don't think it is. The comic pays visual homage to several Amaz. Spidey interior and cover shots (most notably Amaz Spidey 50, with the "Spider-Man No More!" cover), but I can't say that there's a particular story line that the movie directly lifts from. The arc with Harry Osborn seems to be flowing in the direction of the comics, tho that seemed to play out over several years and culminated in Spec Spidey 200.

Yeah, like LD said, the film basicly takes a bunch of ideas from the comics and smashes them together. The Spidey No More times were great though and you can pick them up in the Essentials reprints.

Nope, it's not based on any one story. There are many good Doc Ock stories out there but this one is kind of an amalgam of them all.